We use cookies. Find out more about it here. By continuing to browse this site you are agreeing to our use of cookies.
#alert
Back to search results
New

Senior Manager, Health Economics & Outcomes Research

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Jul 08, 2025

Job Description

Job Summary:

Vertex is seeking a talented individual with the desire to be part of a highly innovative company aimed at transforming the lives of people with serious diseases, their families, and society.

As a Senior Manager and member of our Global HEOR team, your primary responsibility will be to execute on the tactical plan to generate evidence supporting the value proposition of Vertex's CF portfolio of assets. You will contribute to each stage of the development, launch and post-launch phases.

This Senior Manager will report to the Director HEOR, CF. The role will be hybrid, based in Vertex's Boston office in the Seaport District.

Key Responsibilities:

  • Support execution of HEOR evidence generation studies, including prospective and retrospective observational studies, systematic literature reviews, clinical outcome assessment measure development and validation studies, cost-effective analyses, and budget impact models, as needed, to support the asset value
  • Effectively lead external research partners to ensure robust scientific methods are applied to study design and execution and in compliance with all local regulations; be accountable for study design, data analysis and the quality of the evidence produced
  • Support development of product value proposition/value messaging and co-lead development of robust Global launch deliverables (e.g., global value dossier)
  • Provide excellent project management, supporting study team and monitoring external vendors to ensure studies are delivered on time and within budget
  • Develop presentations to communicate complex HEOR evidence to cross-functional internal audiences
  • Clearly communicate study findings to internal and external audiences; lead conference submissions and peer-reviewed publications and ensure evidence is shared appropriately with key stakeholders
  • Act as subject matter expert in HEOR evidence generation across the Global organization

Minimum Qualifications:

  • An advanced degree (e.g., PhD, PharmD, MPH, MS) with an educational focus in a relevant discipline in the areas of health economics or outcomes research
  • Typically requires 5+ years of combined consulting and or biopharmaceutical industry experience in health economics and outcomes research, or the equivalent combination of education and experience
  • Technical expert in HEOR able to formulate and lead complex research projects ensuring that study conduct is technically and scientifically rigorous, reflects best HEOR practices and managed to timelines and budgets
  • Experience executing observational research studies (prospective and/or retrospective)
  • Strong attention to detail and quality focus
  • Exceptional written and verbal communication skills along with the ability to effectively present technical data and complex concepts to diverse audiences
  • A strong track record of publishing in peer reviewed scientific journals and presenting at scientific meetings
  • A track record of success functioning in dynamic, matrix environments with the ability to multi-task seamlessly, balance competing priorities, and communicate proactively with key stakeholders
  • Comprehensive understanding of the legal and regulatory environment of the pharmaceutical industry, with spotless history of compliance and ethical workplace conduct

Pay Range:

$144,000 - $216,000

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

Applied = 0

(web-8588dfb-6jkxz)