Principal Scientist, Drug Metabolism and Pharmacokinetics

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The Opportunity

The Drug Metabolism and Pharmacokinetics (DMPK) department at Genentech is seeking a highly motivated leader who will be supporting small molecule projects in discovery and development.

The DMPK group is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state-of-the-art technologies and sciences of bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings.

The individual would lead the DMPK strategy, design and execute non-clinical studies in a highly collaborative project team environment. Specifically, the individual will be involved in the following activities as part of their role:

• Representation of DMPK at multi-functional discovery and development project teams

• Lead DMPK strategy as it relates to regulatory setting/interactions; author reports/sections for regulatory briefing packages/filings

Who You Are

• You will have a PhD degree in pharmacokinetics, drug metabolism or other relevant fields.

• 2 years of relevant pharmaceutical industry experience as a DMPK project leader.

• Proven scientific expertise in supporting discovery and or development projects.

• Good communication, collaborative and organizational skills and the ability to work in multifunctional teams are essential.

Preferred

• Experience as a member/leader of multi-functional project teams supporting diverse modalities (small/large molecules, peptides, etc.) and modeling skills are highly desired.

Relocation benefits are available for this posting.

The expected salary range for this position based on the primary location of California is $143,200 to $265,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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