Senior Director, Commercial Operations

About INOVIO

INOVIO is a biotechnology company focused on developing and commercializing DNA medicines to help treat and protect people from HPV-related diseases, cancer, and infectious diseases. INOVIO's technology optimizes the design and delivery of innovative DNA medicines that teach the body to manufacture its own disease-fighting tools. For more information, visit www.inovio.com.

Job summary

The Senior Director, Commercial Operations will serve as a key commercial architect supporting the successful launch and commercial execution of INO3107, Inovio's lead product for Recurrent Respiratory Papillomatosis. This leader will be responsible for supporting the design, stand up, and scaling of the commercial infrastructure-spanning KPI creation and monitoring, forecasting, analytics, CRM systems, field operations, and commercial process optimization-to ensure a seamless transition from clinical readiness to commercial excellence. This role is based in our Plymouth Meeting, PA office, with an expectation of working on a hybrid schedule.

As a strategic member of the commercial team, this role will partner closely with Sales, Marketing, Market Access, Finance, Supply Chain, and IT to develop the systems, processes, and insights that equip Inovio's first launch brand for success in the rare disease marketplace.

Essential job functions and duties

Commercial Strategy & Leadership

• Partner with the CCO and leadership team to operationalize commercial strategy aligned with INO3107launchmilestones and revenue goals.
• Develop a scalable infrastructure that supports Inovio's entry into the commercial market, including field deployment planning, incentive design, and governance frameworks.
• Lead launch and annual planning cycles, translating organizational priorities into forecasting models, frameworks, and KPI dashboards.

Forecasting, Analytics & Insights

• Support revenue forecasting, demand modeling, and patientflow analytics in collaboration with Finance and Market Access.
• Develop integrated dashboards to monitor performance across field, brand, patient services, and specialty distribution partners.
• Drive datadriven insights on market uptake, payer dynamics, and HCP engagement patterns to guide strategic adjustments.

Field Operations & Enablement

• In partnership with the Contract Sales Organization (CSO) support field operations infrastructure-including CRM (Salesforce), call planning, territory optimization, and incentive compensation.
• Partner with Sales Leadership to define sales governance, quota methodology, and datadriven targeting aligned with the limited RRP prescriber base.
• In partnership with the Contract Sales Organization (CSO), ensure effective onboarding, training, and field readiness through performance insights, learning tools, and execution dashboards.

Systems, Data, and Reporting Infrastructure

• Own commercial technology, including CRM, BI platforms, and data integration across finance, distribution, and patient services.
• Develop and enforce commercial data governance and validation standards.
• Lead vendor relationships across CRM, analytics, and data aggregation partners to ensure seamless flow of patient and prescriberlevel data.

Team Leadership & CrossFunctional Execution

• As Inovio grows, build and lead a highperforming commercial operations team capable of scaling with Inovio's commercial evolution.
• Foster collaboration across Commercial, IT, Finance, and Clinical teams to ensure smooth integration of data and processes.
• Serve as a commercial operations thought leader-bringing best practices from biotech launches and rare disease environments.

Success Factors

• Strategic and operational balance-equally capable of designing frameworks and executing details.
• Strong analytical acumen and commercial intuition specific to rare disease and buyandbill models.
• Effective crossfunctional communicator and facilitator of collaboration between sciencedriven and commercial teams.
• Handson builder who thrives in a launch environment without legacy infrastructure.

Minimum requirements

• Bachelor's degree in Business, Finance, Life Sciences, or Analytics; advanced degree (MBA, MS, MPH, PharmD) preferred.
• Minimum 10-15 years of progressive experience in commercial operations, analytics, or field enablement, preferably within biotech or rare disease.
• Proven success building and scaling commercial systems in preparation for U.S. product launch.
• Deep familiarity with CRM (Salesforce preferred), incentive compensation platforms, financial modeling, and business intelligence tools (Tableau, Power BI, Snowflake, etc.).
• Demonstrated ability to translate complex data into actionable commercial insights.
• Experience managing thirdparty vendors, distribution partners, and specialty pharmacy networks.
• Strong leadership presence, influencing skills, and the ability to thrive in an entrepreneurial, fastpaced environment.

Disclaimer

INOVIO Pharmaceuticals, Inc. is an Equal Employment Opportunity Employer, including but not limited to veterans and individuals with disabilities. We prohibit discrimination of any kind. In keeping with our policy, we recruit, hire, train, and promote the most qualified individuals for all job titles, and we provide equal opportunities to all employees and applicants for employment.

A current US work authorization is required. The above statements are intended to describe the general nature and level of work being performed by people assigned to this job. They are not to be construed as an exhaustive list of all responsibilities, duties, and skills required of personnel so classified. All personnel may be required to perform duties outside of their normal responsibilities from time to time, as needed. INOVIO offers an attractive benefits package and is an equal opportunity employer.

Important notice to employment businesses/agencies

INOVIO does not accept referrals from employment agencies unless written authorization from the INOVIO Human Resources department has been provided. In the absence of written authorization, any actions undertaken by employment agencies shall be deemed to have been performed without our consent and therefore INOVIO will not be liable for any fees arising from employment agency referrals in respect to current or future position vacancies at INOVIO.