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Sr. Product Manager, Specialty Portfolio & Launches

McKesson Corporation
United States
Mar 13, 2026

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve - we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow's health today, we want to hear from you.

This role offers location flexibility and is open to candidates across the United States.

Candidates based in the Dallas-Fort Worth (DFW) area will be hired in a hybrid capacity and are expected to work onsite at our Headquarters in Irving, TX a minimum of two (2) days per week, with the remaining days worked remotely. Specific in office days may be designated based on team needs and business priorities.

Current Need:

The purpose of the Sr. Product Manager role is to enable, analyze, report on, and track execution of the Specialty generics portfolio strategy, including making data-driven recommendations to optimize portfolio balance and supporting execution of new product launches in the Oncology and Multispecialty clinic channel. The Sr. Product Manager assists the Sr. Director in setting objectives by molecule and manufacturer. This role will monitor portfolio performance to expectations and commitments. Considering market, supply, clinical and financial factors, they will adjust the portfolio to improve performance and/or reduce risk. Launch Execution provides coordination and execution ownership for generic product launches. This role enables launch efficiency and scalability by managing execution of documentation, tracking, preparation, and followthrough.

This role will maintain the core molecule strategies as well as a schedule of product transitions and cost structures. Acting as the primary liaison across multiple internal teams (pricing, sales, purchasing, ClarusOne), they will coordinate timelines and deliverables. The Sr. Product Manager partners closely with Business Development and crossfunctional stakeholders to support launch execution. This role focuses on research, planning, coordination, documentation, tracking, and followthrough to ensure launch decisions are carried out effectively across internal teams.

The ideal candidate is analytical, results oriented, and will be comfortable transitioning between macro-level analysis and detailed execution plans. This role requires an excellent communicator who can build collaborative relationships across a variety of stakeholders. The candidate will be comfortable presenting and supporting their recommendations to senior leaders. Financial acumen and the ability to develop and manipulate models in Excel is essential and prior project management experience is strongly preferred.

Key Responsibilities:

  • Monitor and report on portfolio performance including DIOH, share allocations, margins; communicate variance to the appropriate BDD or internal team

  • Manage portfolio metrics and collaborate with key stakeholders; identify and communicate risks to timelines and deliverables

  • Model and evaluate proposed share re-balances, quarterly market resets, and price advantage opportunities; recommend adjustments

  • Specialty Portfolio cross functional launch execution, market research, governance, risk identification, and delivery of launch strategy. To include new generic and biosimilar launches.

  • Other responsibilities as assigned

Minimum Requirement:

  • Degree or equivalent and typically requires 7+ years of relevant experience.

Critical Skills and Competencies:

  • 7+ years of progressive experience in product management, portfolio management, commercialization, pricing, sourcing, or other related roles

  • Understanding of pharmaceutical supply chain, purchasing and/or distribution concepts

  • Strong business and financial acumen

  • Advanced Excel modeling, including scenario analysis

  • Advanced Smartsheet proficiency with the expectation to grow into a subject-matter expert

  • Working knowledge of Power BI, including development and interpretation of reporting that drives insights, highlights risks and opportunities, and supports clear action items and decisionmaking

  • Ability to coordinate activities across a variety of stakeholders

  • Excellent verbal and written communication skills

  • Ability to function in a fast paced, matrixed environment

Specialized Knowledge & Skills:

  • Portfolio planning and prioritization across molecules, manufacturers, and launch timing

  • Performance monitoring and proactive risk identification with datadriven recommendations

  • Integration of commercial, operational, clinical, and financial factors into portfolio execution

  • Cross functional launch orchestration across commercial, operational, and clinical stakeholders

  • Commercial and financial execution acumen supporting pricing, sourcing, and portfolio decisions

  • Governance, risk management, and delivery discipline in complex, multilaunch environments

Additional Information:

  • Hybrid In-office/Remote

  • Travel up to 30% for conferences, internal meetings, supplier meetings, etc.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, pleaseclick here.

Our Base Pay Range for this position

$121,300 - $202,100

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees, without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age, genetic information, or any other legally protected category. For additional information on McKesson's full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

McKesson welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process. If you require accommodation please contact us by sending an email to Disability_Accommodation@McKesson.com.

Join us at McKesson!

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