Principal Engineer, Office 365 Collaboration & Work Management Platforms

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Apr 17, 2026
Job Description This role owns the modernization of Vertex's collaboration ecosystem, with a strong focus onSharePoint development, site lifecycle management, and enterprise operating models for collaboration services. The individual willhelpdefinehow collaboration platforms are structured, governed, and consumed, while also owning portfoliomanagementtooling and service operations. Our teamoperateswith the ability to enable AI adoption safely, ensuring governance, data protection, and auditability are alwaysmaintainedthroughout ourplatforms. This is both a hands-on technical role and atechnicalowner role, responsible for driving consistency, reducing sprawl, and enabling scalable, secure collaboration across the enterprise. Key Responsibilities 1. SharePoint Development & Site Modernization Lead themodernization of SharePoint site architecture, including templates, provisioning standards, and lifecycle management Define and implementstandardized site patternsfor internal and external collaboration use cases Develop or oversee SharePoint solution automationandAIintegrations to reduce manual processes and improve user experience Establishsite governance controls, including ownership, permissions models, and lifecycle policies Drive improvements tosite provisioning, archiving, and compliance alignment 2. Collaboration Platform Strategy (M365) Act as thetechnical owner for Microsoft 365 collaboration services, including SharePoint, Teams, Exchange, Entra ID, and Copilot Define and execute theroadmap for collaboration services, balancing business enablement with governance and security Partner with InfoSec and IT to ensurecompliance, data protection, and audit readiness 3. Portfolio & Work Management Platform Ownership Own thestrategy, governance, and administrationof Smartsheet, Asana, Planner, and Project Defineclear decision frameworksfor when each platform should be used Establishstandard intake processesfor new requests and initiatives Build and manageportfolio dashboards, reporting, and backlog visibility Ensure alignment between platform capabilities and business outcomes 4. Service Ownership & Operations Operate as theservice owner for collaboration and work management platforms Define and manage: Intake and demand management Backlog prioritization Vendor and service provider oversight (Accenture operations alignment) Ensure strongincident, change, and release management processes Track and improveservice health metrics(adoption, stability, performance) 5. Governance, Standardization & Adoption Establish cleargovernance models across platformsincluding provisioning, access control, and lifecycle management Drivestandardization to reduce tool sprawl and inconsistent usage Lead enablement efforts: training, documentation, and business engagement Promoteresponsible adoption of AI and automation (Copilot)across collaboration services Ideal Candidate Profile Deep hands-on expertise inSharePoint (development + architecture + governance) Strong experience managingenterprise SaaS collaboration platforms (M365) Experience definingservice operating models, intake processes, and governance frameworks Ability to balancebusiness enablement, user experience, and risk management Comfortable managing cross-functional stakeholders Familiarity with AI models, integrations and features Education & Background Bachelor's degree in Information Systems, Computer Science, Business, or equivalent practical experience. Minimum of 6 years experience owning or leading enterprise collaboration, productivity, or work management platforms, with demonstrated progression in scope, influence, and responsibility. #LI-HYBRID Pay Range: $144,000 - $216,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com