Job Title: Research Associate - Biology - II
Duration: 12 Months
Location: Santa Monica, CA
Key Responsibilities
- Culture, quality control (QC), and cell banking of diverse solid tumor cell lines
- Engineer, culture, and characterize CAR T cell function in vitro
- Perform routine laboratory procedures including ddPCR, qPCR, Flow, Luminex/MSD for ELISA, and various cell-based immunoassays and biochemical assays
- Analyze, interpret, and translate results into actionable and tangible findings
- Maintain accurate and detailed records of laboratory procedures, experimental designs, and results in compliance with organizational standards; familiarity with Benchling is a plus
- Design and execute fit-for-purpose or hypothesis-based experiments; analyze and interpret data to support development
- Communicate research plans and results effectively in both oral and written form
- Coordinate tasks across multiple projects and work closely with cross-functional teams to support ongoing research projects, ensuring seamless integration of experimental findings
- Contribute to a dynamic, exciting culture that embraces teamwork and innovation
- Support timeline-sensitive Pre-IND/IND research activities and work cross-functionally with different teams
- Basic Qualifications
- Master's Degree with 2+ years of related industry/academic experience
- OR
- Bachelor's Degree with 4+ years of related industry/academic experience
Preferred Qualifications
- BS with 6+ years or MS with 3+ years or equivalent degree of relevant experience in Cell Biology and/or Immunology
- Prior hands-on experience in the CAR-T field is preferred
- Proficiency in experimental design, data analysis, interpretation, and presentation with a high degree of accuracy and attention to detail
- Hands-on experience with primary T cell isolation, culture, and assays (e.g., cytotoxicity assays, cell proliferation assays, xCELLigence/eSight assays), multicolor flow cytometry, SCLC cell line culture, and data analysis using FACSDiva, FlowJo, GraphPad Prism, and Excel
- Experience with ex vivo CAR T manufacturing is preferred
- Strong written and verbal communication skills
- Flexible and willing to support team priorities and assist team members with projects
|