Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 171 |
Principal Scientist, Research (Targeted Delivery)
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking a Principal Scientist to join a growing team responsible for advancing RNAi therapeutics into the future, by opening up targeted delivery to all tissues. The successful candidate will b...
7h
| Job Type | Full Time |
VP, Business Operations & Partnerships, Clinical Operations
Cambridge, Massachusetts
Overview The Vice President, Business Operations & Partnerships is a critical executive-level role responsible for defining, governing, and scaling the operating model that enables Alnylam's Pipeline Delivery organization to execute on clin...
7h
| Job Type | Full Time |
Senior Manager, Medical Writing
Cambridge, Massachusetts
OVERVIEW: The Senior Manager, Medical Writing will collaborate with project teams on the development of clinical documents in accordance with all applicable regulations, Good Clinical Practices, and Standard Operating Procedures (SOPs) and ...
7h
| Job Type | Full Time |
Associate Director, Regulatory Affairs
Cambridge, Massachusetts
Overview The Associate Director of Regulatory Affairs Strategy will serve as US Regional Lead or Global Regulatory Lead for our early/mid/late-stage CNS programs. The role will lead the regulatory strategy and facilitate submission of data ...
7h
| Job Type | Full Time |
Medical Science Liaison- North Central
Cambridge, Massachusetts
Overview: We are seeking an experienced Medical Science Liaison (MSL) to join the TTR team and support Alnylam's commitment to advancing the science and care of patients with transthyretin (TTR) amyloidosis. Patients often experience prolon...
7h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The People Operations Specialist will be the initial point of contact providing HR support across the organization. This position will be accountable for delivering timely, accurate, and customerfocused service to employees and man...
1d
| Job Type | Full Time |
Associate Director, Clinical Portfolio Technology
Cambridge, Massachusetts
Overview Alnylam isseekinga highly collaborative Associate Director, Clinical Portfolio Technology, to help shape, deliver, and continuously improve technology capabilities that support Clinical Delivery, Portfolio Management, and related D...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Quality Site Head (Norton) Overview The Quality Site Head will lead the Quality organization for the Norton Manufacturing and Testing Facility. This role serves as the senior Quality leader for the site, accountable for building and sustain...
1d
| Job Type | Full Time |
Senior Associate Scientist, Ligand Discovery
Cambridge, Massachusetts
Overview: The Delivery Sciences team at Alnylam is seeking a Senior Associate Scientist to contribute to our ligand discovery efforts for expanding RNAi delivery to all tissues. The successful candidate will help drive in vitro ligand selec...
1d
| Job Type | Full Time |
Associate Scientist II, Next Wave Biology
Cambridge, Massachusetts
Overview: The Next Wave Biology group is seeking a motivated candidate to fill an Associate Scientist II position to join our dynamic, fast-paced and interdisciplinary team. This position is an opportunity to potentially see one's work prog...
1d
| Job Type | Full Time |